The Key Laboratory of Structural Biology of Zhejiang Province currently has 16 principal investigators. One focus of the Key Laboratory is structural biology studies carried out to understand the assembly and regulation of biomacromolecular machines and the structure-function relationship of membrane proteins. Interdisciplinary studies between structural biology and other disciplines such as protein design, medicinal chemistry, and proteomics are the other focus of the Key Laboratory, with the aims of understanding the molecular mechanisms underlying the initiation and progression of human diseases and accelerating the development of effective treatments.